Biomedical Engineering Archives

Samhita Vasu graduated from Johns Hopkins Engineering on a Hodson Trust Scholarship with a BS in biomedical engineering in May 2024. She is interested in the use of microphysiological systems, medical device design, data science, and signal processing to help understand, diagnose, and treat life-threatening diseases. At Johns Hopkins, she worked on heart-on-chip assays for Duchenne muscular dystrophy (DMD) drug screening, as well as on the use of engineered heart tissues to study mitochondrial dysfunction in DMD; she also studied the neurodevelopmental outcomes of renal anhydramnios fetal therapy. Besides, she worked in Stanford’s Cardiac MRI Research Group to study cardiac MRI texture analysis for better tracking of the disease progression of DMD. As an intern for NASA Ames Research Center, she developed a spaceflight environmental data visualization tool for the Rodent Research missions to the International Space Station. Apart from research, Samhita was involved in the Johns Hopkins’ Biomedical Engineering Design Teams program, through which she designed, built, and validated various medical devices and solutions. One such project involved building a flexible arthroscope to increase visualization to the posterior compartment of the knee. Another project involved building a more precise shave biopsy device to prevent melanoma transection. She also led a team to develop a generative AI, image-based medical information translation solution for patients with low English proficiency. Samhita was the first author of an article titled “Biomaterials-based Approaches for Cardiac Regeneration” and was also awarded the Dr. Stanley Hellerstein Memorial Travel Award.

Chronic kidney disease (CKD) is a debilitating condition that impacts around 140 million people in India. Fifty per cent of patients with CKD in India are first seen by a healthcare professional when their disease has progressed to the extent of kidney failure. Given India’s low physician-to-patient ratio, at-home monitoring can expedite diagnosis and improve treatment. In her Fulbright-Nehru project, Samhita is working with CKD specialists to design and validate a saliva-based creatinine sensor that can measure kidney function at home. The goal is to develop a working device that helps catch CKD symptoms early in at-risk patients.

Harini Kannan is a student at Harvard University, graduating in Spring 2024 with a BS in mechanical engineering. Her interests lie at the intersection of engineering and medicine, with a specific emphasis on pediatrics and neurodevelopment. This is driven by her research in the following areas: development of robotic wearable systems for rehabilitation; assessing early mobility in global hospitals; volunteer work with underprivileged children in Cambridge and Boston communities; and organizing recreational programs for children with disabilities. She hopes to pursue a career in medicine and develop medical devices to help pediatric populations.

Harini’s Fulbright-Nehru project is building upon her experience working with children with cortical visual impairment (CVI) where it is difficult to identify its symptoms when it’s present alongside autism. For her research, she is working with the Low Vision Center at Aravind Eye Institute, Madurai, to develop the first autism-standardized CVI diagnostic tool and implement it. Using the currently administered assessments, she is identifying the visual skill impairments with the highest correspondence to a CVI diagnosis. She is also developing an app in the form of a mobile game to act as at-home visual rehabilitation to improve visual abilities that are impacted by CVI.